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  • BSI
    BS ISO 20391-2:2019 Biotechnology. Cell counting - Experimental design and statistical analysis to quantify counting method performance
    Edition: 2019
    $497.46
    / user per year

Description of BS ISO 20391-2:2019 2019

This document provides a method for evaluating aspects of the quality of a cell counting measurement process for a specific cell preparation through a set of quality indicators derived from a dilution series experimental design and statistical analysis. The quality indicators are based on repeatability of the measurement and the degree to which the results conform to an ideal proportional response to dilution. This method is applicable to total, differential, direct and indirect cell counting measurement processes, provided that the measurement process meets the criteria of the experimental design (e.g. cells are suspended in a solution).

This method is most suitable during cell counting method development, optimization, validation, evaluation and/or verification of cell counting measurement processes.

This method is especially applicable in cases where an appropriate reference material to assess accuracy is not readily available. This method does not directly provide the accuracy of the cell count.

This method is primarily applicable to eukaryotic cells.

NOTE

Several sector/application specific international and national standards for cell counting exist. Where applicable, consulting existing standards when operating within their scope can be helpful.



Standard NumberBS ISO 20391-2:2019
TitleBiotechnology. Cell counting - Experimental design and statistical analysis to quantify counting method performance
StatusDefinitive
Publication Date2019-09-05
Identical National Standard OfISO 20391-2
DescriptorsPerformance, Analysis, Experimental design, Counting, Biotechnology
ICS07.080 Biology. Botany. Zoology
CommitteeBTI/1
ISBN978 0 580 94246 4
PublisherBSI
Pages62

About BSI

BSI Group, also known as the British Standards Institution is the national standards body of the United Kingdom. BSI produces technical standards on a wide range of products and services and also supplies certification and standards-related services to businesses.
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